The G4 Society (G4S) is an voluntary-based non-profit organization of researchers worldwide that promotes communication for the advancement of interdisciplinary nucleic acids research and technology.
Papers of Interest
Chapter by F. Brad Johnson “Fundamentals of quadruplexes and their biology” read in book
Commentary by Prof. Chaires
G-quadruplexes (G4) have evolved from being a biophysical oddity to being structures of functional significance in biology. For the chemist or physical scientist, appreciation of the possible roles of G4 structures in biology can be difficult because of the scientific cultural divide. Biologists speak a different language. This outstanding review by Brad Johnson presents an insightful and crystal-clear overview G4 biology. It is particularly helpful that he offers explanations of the methods used for studies of G4s in biology, and points out the strengths, weaknesses and potential problems with each approach. As a biophysicist, I have struggled to keep up with, and understand, the rapid advances in G4 biology. This is the most helpful and insightful review of the subject I have ever seen.
G-Quadruplexes act as sequence-dependent protein chaperones.
read recommendation by Jean-Louis Mergny
Begeman A., Son A., Litberg T. J., Wroblewski T. H., Gehring T., Huizar Cabral V., Bourne J., Xuan Z., and Horowitz S.
Single-molecule visualization of DNA G-quadruplex formation in live cells. read
Di Antonio M., Ponjavic A., Radzevičius A., Ranasinghe R. T., Catalano M., Zhang X., Shen J., Needham L., Lee S. F., Klenerman D., and Balasubramanian S.
Landscape of G-quadruplex DNA structural regions in breast cancer. read
Hänsel-Hertsch R., Simeone A., Shea A., Hui. W. W. I., Zyner K. G., Marsico G., Rueda O. M., Bruna A., Martin A., Zhang X., Adhikari S., Tannahill D., Caldas C., and Balasubramanian S.
A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution. read
Paudel B. P., Moye A. L., Abou Assi H., El-Khoury R., Cohen S. B., Holien J. K., Birrento M. L., Samsorn S., Intharapichai K., Tomlinson C. G., Teulade-Fichou M. P., González C., Beck J. L., Damha M. J., van Oijen A. M., and Bryan T. M.
33rd International Conference on Antiviral Research (ICAR) read
Changed to webinars that will take place this fall from September to December 2020 and will be free-of-charge to all ISAR members.
Quadruplexes Made in France
Institut Pasteur Auditorium François Jacob, Paris.
Postponed to 2021
Advances in Noncanonical Nucleic Acids 2020 (ANNA 2020)
Gozd Martuljek, Slovenia, October 1-3, 2020. Cancelled.
8th International Meeting on Quadruplex Nucleic Acids, 2021
Pittsburg, USA – to be announced soon
Nucleic Acid Secondary Structures G4s and Beyond
To participate, send email to G4webinarseries@gmail.com.
Free Access (up to 300 participants).
Nucleic Acid Secondary Structures G4s and Beyond for Postdocs and PhD Students
Send your talk by November 5, 2020
Current Special Issue Deadline
15 December, 2020
Molecules journal: "NMR in the Drug Design". read